Biocompatible and degradable scaffolds based on 2-hydroxyethyl methacrylate, gelatin and poly(beta amino ester) crosslinkers
نویسندگان
چکیده
منابع مشابه
Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as cross-linker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved transluc...
متن کاملCharacterization of poly(2-Hydroxyethyl Methacrylate) Scaffolds for Tissue Engineering
Physical properties of scaffolds intended for myocardial tissue regeneration were studied. Mechanical properties and degradation rates were evaluated for degradable scaffolds composed of poly (2-hydroxyethyl methacrylate) (pHEMA) crosslinked with polycaprolactone (PCL). pHEMA copolymerized with tetraethylene glycol as a crosslinker served as a control. Fibroblast cells were used for cytotoxicit...
متن کاملStudies on the Thermo-Mechanical Properties of Gelatin Based Films Using 2-Hydroxyethyl Methacrylate by Gamma Radiation
Gelatin films were prepared by casting. Tensile strength (TS) and elongation at break (Eb) of the gelatin films were found to be 46 MPa and 3.5%, respectively. Effect of gamma radiation (Co-60) on the thermo-mechanical properties of the gelatin films was studied. 2-hydroxyethyl methacrylate (HEMA) was added to the gelatin during casting varying (10% 30% by weight) and found to increase the TS s...
متن کاملFeedback-regulated paclitaxel delivery based on poly(N,N-dimethylaminoethyl methacrylate-co-2-hydroxyethyl methacrylate) nanoparticles.
pH-Sensitive poly(N,N-dimethylaminoethyl methacrylate (DMAEMA)/2-hydroxyethyl methacrylate (HEMA)) nanoparticles were prepared for the triggered release of paclitaxel within a tumor microenvironment. Tumors exhibit a lower extracellular pH than normal tissues. We show that paclitaxel release from DMAEMA/HEMA particles can be actively triggered by small, physiological changes in pH (within 0.2-0...
متن کاملThe effect of polar copolymers in protein absorption on contact lenses on 2-Hydroxyethyl methacrylate(HEMA)
For the purpose of increasing the permeability to oxygen and equilibrium water content in contact lenses, polar copolymers with nonionic monomers such as 2-hydroxyethle methacrylate(HEMA) Is used. By adding the polar monomers to (HEMA), the permeability to oxygen and equilibrium with water content is increased and also the absorption of proteins on lens surface is changed. In this research, the...
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ژورنال
عنوان ژورنال: Polymer Testing
سال: 2018
ISSN: 0142-9418
DOI: 10.1016/j.polymertesting.2018.04.024